Rashford teed up the first of Jesse Lingard’s two goals in South Wales and keeps his place with Anthony Martial dropping to the bench. At the back there are recalls for Eric Bailly and Phil Jones after injury as United go with a back three.
However, Mauricio Pochettino has sprung a surprise by reverting from his own back three. While Harry Kane misses out as expected due to a hamstring injury, Davinson Sanchez also sits out as Spurs switch to a back four with Eric Dier and Harry Winks set to start ahead of the defence in a 4-2-3-1 formation.
Man Utd: De Gea; Bailly, Smalling, Jones; Valencia, Herrera, Matic, Young; Mkhitaryan, Rashford; Lukaku. Subs: Mata, Martial, Lingard, Blind, Romero, Darmian, McTominay.
Tottenham: Lloris; Aurier, Alderweireld, Vertonghen, Davies; Dier, Winks; Sissoko, Alli, Eriksen; Son. Subs: Trippier, Rose, Sanchez, Vorm, Nkoudou, Llorente, Dembele.